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GENOMICS IN CANCER

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CHAPTER ONE

1.0     Introduction

1.1     Etiology of Cancer

CHAPTER TWO

2.0     Genome-Scale Approaches

2.1     Genomics of Tumor Profiling

2.2.1  Immunohistochemistry

2.1.2  Microsatellite Instability

2.1.3  Microarray Analysis and Global Expression Analysis

2.2     Single Nucleotide Polymorphisms (SNP)

2.2.1  SNPs and cancer gene identification, cancer risk, prognosis, and comorbidities

2.2.2  SNP and Drug Responses-Interactions and Pharmacogenomics

2.3     Epigenetics

2.4     Genome-scale sequencing

2.5     Regulatory genomics

2.6     Functional screening

CHAPTER THREE

3.0     Integrative Cancer Genomics

3.1     Meta-analysis and expression signatures

3.2     Caveats

CHAPTER FOUR

4.0     Conclusion

References


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