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GAMMA-AMINOBUTYRIC ACID (GABA)

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CHAPTER ONE

1.0     Introduction

1.1     Amino-butyric acid

1.1.1  Biochemistry and Pharmacokinetics

1.1.2  Mechanism of action

1.1.3  Deficiency States

CHAPTER TWO

2.0     The major inhibitory neurotransmitter in nervous system

2.1     Physiology and Pharmacology of GABAA ,GABAB, GABAC Receptors

2.1.1  Structure and function of GABAA Receptors

CHAPTER THREE

3.0     Metabolism of plants

3.1     Glutamate Decarboxylase

3.2     transaminase

3.3     Succinic semialdehyde dehydrogenase

3.4     γ- Hydroxybutyric acid

3.5     shunt and the metabolism of nitrogen

3.5.1  Impact of   shunt on the nitrogen metabolism

3.5.2  Regulation of shunt by nitrogen availability

CHAPTER FOUR

4.0     Clinical application

4.1     Side effects and toxicity

CHAPTER FIVE

5.0     Conclusion

References


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