This project has been able to carry out Small and Medium Scale business enterprises and economic growth. The research sample is randomly selected from De Eugene De-Rose Industry and Vono Product Plc by survey method composed of thirty (30) respondents. Chapter one looked at the background of the study (introduction), the statement of problems, objective of study. It also highlights research questions, statement of hypothesis, significance of the study, scope of the study, limitation of the study, history of the case study and definitions of terms. Chapter two was based on literature review and relevant texts on the subject topic. Chapter three outlined the research methodology used in conducting the research work. It indicates that this research work was carried out using the survey research method. The use of questionnaire and personal interview in collecting relevant data was adopted. Chapter four gives the data analysis, interpretation and presentation of data collected; it also includes the test of hypotheses. Finally, chapter five brings the research work to a conclusion by giving a summary of findings, conclusion and recommendations.Therefore, through the hypotheses tested it was concluded through chi-square statistical package that –There is a significant correlating between small and medium scale and economic growth of Nigeria.