This study has examined the relevance of Information Technology on e-Business processes of SMEs, using DirectXplanation.com Nigeria Limited as a case study, where the primary data was obtained. The total sample size was 138 since 150 questionnaires were administered and 138 were retrieved from the organization, the Basic research design was survey method and questionnaire was used as a data instrument. The research hypotheses were tested using Chi-square statistical (SPSS). The analysis of the research hypotheses indicated the following: that IT plays an important role in the increase of productivity and economic activities and IT does not only help in increasing productivity but also quality and make the way business operate less complicated, time saving, and disclose the new trends of business and how business are supposed to address changes, IT has a great influence on different business processes, and investment on IT has improved efficiently and effectively on e-business.
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