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Department of Bio-Chemistry | Final Year Research Project Topics | Download Free Projects

  • 1. PURIFICATION AND CHARACTERIZATION OF RHODANESE FROM THE LIVER OF MANGO TILAPIA (...

    » ABSTRACT Rhodanese, a ubiquitous enzyme, catalyzes the detoxification of cyanide by sulphuration reaction. Cyanide is a highly toxic substance and an ineffective detoxification of this substance may lead to inhibition of respiration, production of ATP and its dependent processes, liver damage and necrosis in aquatic organisms. Considering the habitat of this fish which is a reservoir, it is expose...Continue Reading »

    65 pages |  124 engagements | 

  • 2. PHYTOCHEMICAL CONSTITUENTS OF THE HEXANE EXTRACT OF CEIBA PENTANDRA PLANT (TOTOR...

    » ABSTRACT Ceiba pentandra (totoro) is a plant that is very popular in African Traditional medicine and it belongs to the family of Bombacaceae. The matured tree is as much as 56 m high, with long cylindrical and huge buttresses to 8 m high and wide spreading. It is the largest tree of the West African region and it occurs throughout the continent. Qualitative analysis indicated that the leaves co...Continue Reading »

    65 pages |  117 engagements | 

  • 3. PHYTOCHEMICAL CONSTITUENTS AND ANTIOXIDANT ACTIVITIES OF THE CHLOROFORM EXTRACT ...

    » ABSTRACT Since ages, many plants have been used for preservative and medicinal purposes due to the presence of secondary metabolites referred as Phytochemicals. Phytochemicals are biologically active plant compounds having disease hampering capabilities and preservative action. The genus Ocimumcontains more than 200 species of herbs and shrubs which have been shown to have medicinal properties an...Continue Reading »

    65 pages |  126 engagements | 

  • 4. PARTIAL PURIFICATION AND EFFECT OF TEMPERATURE AND HEAT STABILITY STUDIES ON RHO...

    » ABSTRACT The research is aimed at investigating the effect of temperature and heat stability of Rhodanese from the Liver of a local goat.  This research shows the existence of rhodanese from a local goat liver homogenate. It was observed that the enzyme was partially purified by ammonium sulphate precipitation and dialysis. The specific activity of enzyme after partial purification using ammonium...Continue Reading »

    65 pages |  109 engagements | 

  • 5. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIVER, HEART AND PLAS...

    » ABSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Electrolytes status were analysed in the plasma, liver and heart after four weeks of feeding.   The liver being the organ where major metabolisms take place and...Continue Reading »

    65 pages |  107 engagements | 

  • 6. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIVER AND PLASMA ELEC...

    » ABSTRACT Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. Sixty (60) albino rats were used to study the effect vegetables extracts modified diets; grouped into, one group was fed with high sucrose diet while others were fed with normal ratchow. After 3weeks of feeding respective vegetable extracts w...Continue Reading »

    65 pages |  104 engagements | 

  • 7. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIVER FUNCTION TEST (...

    » ABSTRACT Vegetables and fruit provide a significant part of human nutrition, as they are important sources of nutrients, dietary fibre, and phytochemicals. Sixty (60) albino rats were used to study the effect vegetables extracts modified diets; grouped into, one group was fed with high sucrose diet while others were fed with normal ratchow. After 3weeks of feeding respective vegetable extracts w...Continue Reading »

    65 pages |  90 engagements | 

  • 8. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON LIPID PROFILE (TOTAL ...

    » AABSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Lipid profile status were analysed in the plasma, brain and kidney after four weeks of feeding.   The brain revealed a significant (p...Continue Reading »

    65 pages |  99 engagements | 

  • 9. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ANTIOXIDANTS AND MALO...

    » ABSTRACT This present study was aimed at investigating the effect of the processing methods (Juice and Shaft) on oxidative stress induced by high sucrose diets on Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the heart, brain and plasma. The juice and shaft extract of Telferia occidentalis(Ugwu) and Vernonia amygdalina (Ewuro) vegetables were processed and were administered a...Continue Reading »

    65 pages |  110 engagements | 

  • 10. EFFECT OF METAL IONS ON ARGINASE FROM THE KIDNEY OF LOCAL GOAT (Capra aegagrus h...

    » ABSTRACT This research is aimed at isolating, partially purifying and determination of arginase from the kidney of a local goat. Methods used in the isolation and partial purification of the enzyme include; Ammonium sulphate precipitation, dialysis.etc. Result from this work showed that arginase isolated from a local goat has a specific activity of 0.358 with a yield of 12.12% incubation of the en...Continue Reading »

    65 pages |  89 engagements | 

  • 11. EFFECTS OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ANTIOXIDANTS (SUPERO...

    » ABSTRACT This study was aimed at investigating the effect of vegetable extract (Juice and pulp) on oxidative stress induced by high sucrose diets on specific antioxidants such as (Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the liver, brain and plasma. 60 albino wistar strain rats were used, The rats were shared into two groups, one part fed with high sucrose diet while others...Continue Reading »

    65 pages |  72 engagements | 

  • 12. DISTRIBUTION OF THIAMINASE IN DIFFERENT TISSUES OF SOME FISH SPECIES

    » ABSTRACT Thiaminase degrade thiamine into separate thiazole and pyrimidine moieties, an enzyme that cleaves vitamin B1 and are sporadically distributed among prokaryotes and eukaryotes. The excess thiaminase in fish tissues causes thiamine deficiency syndrome like neurological and cardiac disorder, it also causes reproductive disorder in fishes and finally leads to death. Thiaminase in human cause...Continue Reading »

    65 pages |  86 engagements | 

  • 13. DETERMINATION OF ALKALINITY OF SACHET AND BOREHOLE WATER

    » ABSTRACT Studies have shown that alkaline water helps neutralize acids in the body and allows for the free passage of substrate. The alkalinity of selected sachet and borehole water in Remo land were determined and the water samples were subsequently alkalised with the use of energy cup. The untreated SW4 sachet water has the highest pH meter value of (7.2) and a pH colour chat value of (8.0) whil...Continue Reading »

    65 pages |  96 engagements | 

  • 14. DERMATOGLYPHIC APPRAISAL OF STUDENTS

    » ABSTRACT  The study was conducted at the faculty of Basic of Medical Sciences, Remo Campus to evaluate the dermatoglyphic appraisal of male students. Fingerprints of 50 male students within the age range of 19 to 24 years were used for this study. All healthy individuals with no history of any genetic disorders were included in the study. Ink method as described by Cummins and Midlo, which requir...Continue Reading »

    65 pages |  72 engagements | 

  • 15. COMPARATIVE HYPOLIPIDEMIC EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALIN...

    » ABSTRACT The importance of vegetables in human nutrition cannot be overemphasized, as they are important sources of nutrients, dietary fibre, and phytochemicals. However, the bioavailability of these nutritive values and palatability among other reasons has set certain barriers in their consumption. This work investigated utilized 60 wistar rats fed with different diet composition such as high su...Continue Reading »

    65 pages |  77 engagements | 

  • 16. CHARACTERIZATION OF ARGINASE FROM THE LIVER OF MANGO TILAPIA (Sarotherodongalila...

    » BSTRACT Arginase is a detoxifying enzyme that catalyses the hydrolysis of arginine into ornithine and urea, the last step of urea cycle a process through which the body disposes off harmful ammonia. This research was carried out to determine the characteristics of liver arginase of mango tilapia (Sarotherodongalilaeus) in Opa river, Osun state. The enzyme ‘arginase’ was isolated from the liver...Continue Reading »

    65 pages |  72 engagements | 

  • 17. ACTIVITIES OF RESPIRATORY COMPLEX TWO ON THE LIVER OF NORMAL AND PROTEIN UNDERNO...

    » ABSTRACT In this attempt to investigate the effect the activities of respiratory complex II in the liver of normal and protein undernourished male weaning rats fed with diets containing coconut oil twenty rats were used. They were grouped into four (5 rats in each and fed with normal diets, low protein diets containing 5% casein, normal with coconut oil substituting to vegetable oil and low protei...Continue Reading »

    65 pages |  103 engagements | 

  • 18. ACTIVITIES OF Na+ K+-ATPase IN THE LIVER OF NORMAL AND PROTEIN UNDERNOURISHED RA...

    » ABSTRACT The attempt of this study is to investigate the activities of sodium potassium ATPase in the liver of normal and protein undernourished male weaning rats fed with diets containing coconut oil.  Twenty weaning male rats were grouped into four groups, five rats for each. Group A were fed with normal diets, Group B were fed with low protein diets containing 5% casein, Group C were fed with ...Continue Reading »

    65 pages |  101 engagements | 

  • 19. ACTIVITIES OF CYTOCHROME OXIDASE IN THE RAT LIVER OF NORMAL AND PROTEIN UNDERNOU...

    » ABSTRACT The study was carried out to investigate the activities respiratory complex IV in the liver of normal and protein undernourished wistar rats fed with cassava peel.  Twenty weaning male rats were grouped into four groups, five rats for each. Group A were fed with normal diets, Group B were fed with low protein diets containing 5% casein, Group C were fed with normal diets and coconut oil ...Continue Reading »

    65 pages |  96 engagements | 

  • 20. EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ELECTROLYTES (CALCIUM...

    » CBSTRACT Sixty (60) albino rats of the wistar strain were used to investigate the effect different vegetables extracts modified diets; shared into two groups, one part fed with high sucrose diet while others were fed with normal ratchow. Electrolytes status were analysed in the plasma, liver and heart after four weeks of feeding.   Feeding of rats with high sucrose diet revealed a significant (p...Continue Reading »

    65 pages |  99 engagements | 


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